For reprints etc – go to:


MS Llewellyn, S Leadbeater, C Garcia, FE Sylvain, M Custodio, KP Ang, et al 2017
Parasitism perturbs the mucosal microbiome of Atlantic Salmon
Scientific reports 7, 43465MS Llewellyn, P McGinnity, M Dionne, J Letourneau, F Thonier, et al 2016 The biogeography of the atlantic salmon (Salmo salar) gut microbiome. 2016 The ISME journal 10 (5), 1280-1284

FÉ Sylvain, B Cheaib, M Llewellyn, TG Correia, DB Fagundes, AL Val, et al 2016 pH drop impacts differentially skin and gut microbiota of the Amazonian fish tambaqui (Colossoma macropomum) Scientific reports 6

N Derome, J Gauthier, S Boutin, M Llewellyn – The Rasputin Effect: When Commensals and Symbionts Become Parasitic in Bacterial opportunistic pathogens of fish p81-108

N Derome, J Gauthier, S Boutin, M Llewellyn The Rasputin Effect: When Commensals and Symbionts Become Parasitic, in Fungal Secondary Invaders of Fish p109-126

MS Llewellyn, S Boutin, SH Hoseinifar, N Derome 2016 Teleost microbiomes: the state of the art in their characterization, manipulation and importance in aquaculture and fisheries. Frontiers in microbiology 5


MA Dario, RMM da Rocha, P Schwabl, AM Jansen, MS Llewellyn Small subunit ribosomal metabarcoding reveals extraordinary trypanosomatid diversity in Brazilian bats. PLoS neglected tropical diseases 11 (7), e0005790

LE Hernandez-Castro, M Paterno, AG Villacís, B Andersson, JA Costales, M Grigalva, MS Llewellyn 2017 2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador PLOS Neglected Tropical Diseases 11 (7), e0005710

N Acosta, E Lopez, MD Lewis, MS Llewellyn, A Gomez, F Roman, et al 2017 Hosts and vectors of Trypanosoma cruzi discrete typing units in the Chagas disease endemic region of the Paraguayan Chaco Parasitology 144 (7), 884-898

P Schwabl, MS Llewellyn, EL Landguth, B Andersson, U Kitron, M Grijlava 2017 Prediction and prevention of parasitic diseases using a landscape genomics framework
Trends in parasitology 33 (4), 264-275

Costales, JA Kotton CN Zurita-Leal AC Garcia-Perez J Llewellyn MS Messenger, LA Bhattacharyya T Burleigh BA Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcI DOM ) Parasites & Vectors 2015, 8:435

Pennington PM, Messenger LA, Reina J, Juárez JG, Lawrence GG, Dotson EM, Llewellyn MS, Cordón-Rosales C. 2015 The Chagas disease domestic transmission cycle in Guatemala: Parasite-vector switches and lack of mitochondrial co-diversification between Triatoma dimidiata and Trypanosoma cruzi subpopulations suggest non-vectorial parasite dispersal across the Motagua valley. Acta Trop. In press

Costales JA, Jara-Palacios MA, Llewellyn MS, Messenger LA, Ocaña-Mayorga S, Villacís AG, Tibayrenc M, Grijalva MJ. Trypanosoma cruzi population dynamics in the Central Ecuadorian Coast. Acta Trop. 2015 In press

Llewellyn, MS Messenger, LA Luquetti A, Garcia L, Torrico F, Tavares, S Cheaib, B Derome, N Delepine, M Baulard, C Deluze, JF Sauer, S Miles, MA 2015 Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.PLoS NTDs 7;9(4):e0003458

Messenger, LA; Garcia, AL; Vanhove, M; Huaranca, C; Bustamante, M; Torrico, M; Torrico, F; Miles, MA; Llewellyn, MS 2015 Ecological host fitting of Trypanosoma cruzi TcI in Bolivia: mosaic population structure, hybridization and a role for humans in Andean parasite dispersal. Molecular Ecology. ;24(10):2406-22

Messenger LA, Yeo M, Lewis MD, Llewellyn MS, Miles MA. 2014 Molecular Genotyping of Trypanosoma cruzi for Lineage Assignment and Population Genetics. Methods Mol Biol. 1201:297-337.

Diosque P, Tomasini N, Lauthier JJ, Messenger LA, Monje Rumi MM, Ragone PG, Alberti-D’Amato AM, Pérez Brandán C, Barnabé C, Tibayrenc M, Lewis MD, Llewellyn MS, Miles MA, Yeo M. 2014 Optimized multilocus sequence typing (MLST) scheme for Trypanosoma cruzi. PLoS Negl Trop Dis. 8:e3117

Ramírez JD, Llewellyn MS. 2014 Reproductive clonality in protozoan pathogens – truth or artefact? Molecular Ecology 23: 4195–4202,

Baleela, R Llewellyn MS Fitzpatrick, S Kuhls, K Schönian, G Miles MA Mauricio IL 2014 Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. Parasites and Vectors 7:496

Lima, V. Jansen, AM, Messenger, LM. Miles, MA. Llewellyn, MS. 2014 Wild Trypanosoma cruzi I genetic diversity in Brazil suggests admixture and disturbance in parasite populations from the Atlantic Forest region. Parasites and Vectors 7:263

Segovia M, Carrasco HJ, Martínez CE, Messenger LA, Nessi A, Londoño JC, Espinosa R, Martínez C, Alfredo M, Bonfante-Cabarcas R, Lewis MD, de Noya BA, Miles MA, Llewellyn MS. 2013 Molecular epidemiologic source tracking of orally transmitted Chagas disease, Venezuela. Emerg Infect Dis. 19:1098-101

Tomasini N, Lauthier JJ, Llewellyn MS, Diosque P. 2013 MLSTest: novel software for multi-locus sequence data analysis in eukaryotic organisms. Infect Genet Evol. 20:188-96.

Zumaya-Estrada FA, Messenger LA, Lopez-Ordonez T, Lewis, MD , Flores-Lopez CA, Martínez-Ibarra JA, Pennington PM, Cordon-Rosales C, Carrasco HJ, Segovia M, Miles MA,  Llewellyn MS 2012 North American import? Charting the origins of an enigmatic Trypanosoma cruzi domestic genotype. Parasites and Vectors. 5:226 doi:10.1186/1756-3305-5-226

Franzén, O. Talavera-López, C. Ochaya, S. Butler, CE.  Messenger, LA.  Lewis, MD. Llewellyn, MS. Marinkelle, CJ Tyler, KM  Miles MA, Andersson BA (2012) Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei. BMC Genomics. 13:531

Ramírez, JD, Guhl, F, Messenger, LA, Lewis, MD, Montilla, M, Cucunuba, Z, Miles, MA; Llewellyn, MS. (2012) Contemporary cryptic sexuality in Trypanosoma cruzi. Molecular Ecology. 21: 4216–4226,

Carrasco HJ, Segovia M, Llewellyn MS, Morocoima A, Urdaneta-Morales S, et al. (2012) Geographical Distribution of Trypanosoma cruzi Genotypes in Venezuela. PLoS Negl Trop Dis 6(6): e1707.

Lauthier JJ, Tomasini N, Barnabé C, Rumi MM, D’Amato AM, Ragone PG, Yeo M, Lewis MD, Llewellyn MS, Basombrío MA, Miles MA, Tibayrenc M, Diosque P. (2012) Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: validation using parasite stocks from the Chaco Region and a set of reference strains. Infect Genet Evol. 12(2):350-8

Messenger LA, Llewellyn MS, Bhattacharyya T, Franzén O, Lewis MD, et al. (2012) Multiple Mitochondrial Introgression Events and Heteroplasmy in Trypanosoma cruzi Revealed by Maxicircle MLST and Next Generation Sequencing. PLoS Negl Trop Dis 6(4): e1584  doi:10.1371/journal.pntd.0001584

Zingales B, Miles MA, Campbell DA, Tibayrenc M, Macedo AM, Teixeira MM, Schijman AG, Llewellyn MS, Lages-Silva E, Machado CR, Andrade SG, Sturm NR.(2012) The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infect Genet Evol.12:240-53

Llewellyn, M.S.,Rivett-Carnac, J.B., Fitzpatrick, S., Lewis, M. D., Yeo, M., Gaunt M.W., Miles M.A., Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection. Int J Parasitol. 41(6):609-14.

Franzen, O. Ochaya, S. Sherwood, E. Lewis, M. Llewellyn, M. 2011Miles, M. Andersson, B. 2011 Shotgun Sequencing Analysis of Trypanosoma cruzi I Sylvio X10/1 and comparison with T. cruzi VI CL Brener. PLoS Negl Trop Dis 5(3):e984

Yoshida, N. Tyler K.M., Llewellyn, M.S.2011Invasion mechanisms among emerging food borne protozoan parasites. Trends in Parasitology. 27(10):459-66

Yeo M, Mauricio IL, Messenger LA, Lewis MD, Llewellyn MS, Nidia Acosta1,Tapan Bhattacharyya, Patricio Diosque, Hernan J. Carrasco, Michael A. Miles (2011) Multilocus Sequence Typing (MLST) for Lineage Assignment and High Resolution Diversity Studies in Trypanosoma cruzi. PLoS Negl Trop Dis 5(6): e1049.

Ocaña-Mayorga S, Llewellyn MS, Costales JA, Miles MA, Grijalva MJ, 2010 Sex, Subdivision, and Domestic Dispersal of Trypanosoma cruzi Lineage I in Southern Ecuador. PLoS Negl Trop Dis 4(12): e915.

Hamilton, P.B., Lewis, M.D., Cruickshank, C., Gaunt, M.W., Yeo, M., Llewellyn, M.S.,Valente, S.A., Maia da Silva, F., Stevens, J.R., Miles, M.A., Teixeira, M.M., 2010 Identification and lineage genotyping of South American trypanosomes using fluorescent fragment length barcoding. Infect Genet Evol 11, 44-51.

Bhattacharyya, T., Brooks, J., Yeo, M., Carrasco, H.J., Lewis, M.D., Llewellyn, M.S., Miles, M.A., 2010 Analysis of molecular diversity of the Trypanosoma cruzi trypomastigote small surface antigen reveals novel epitopes, evidence of positive selection and potential implications for lineage-specific serology. Int J Parasitol. 40(8):921-8

Llewellyn, M.S.,Miles, M.A., Carrasco, H.J., Lewis, M.D., Yeo, M., Vargas, J., Torrico, F., Diosque, P., Valente, V., Valente, S.A., Gaunt, M.W., 2009. Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. PLoS Pathog 5, e1000410.

Llewellyn, M.S., Lewis, M.D., Acosta, N., Yeo, M., Carrasco, H.J., Segovia, M., Vargas, J., Torrico, F., Miles, M.A., Gaunt, M.W., 2009. Trypanosoma cruzi IIc: Phylogenetic and Phylogeographic Insights from Sequence and Microsatellite Analysis and Potential Impact on Emergent Chagas Disease. PLoS Negl Trop Dis 3, e510.

Lewis, M.D., Llewellyn, M.S., Gaunt, M.W., Yeo, M., Carrasco, H.J., Miles, M.A., 2009. Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids. Int J Parasitol 39, 1305-1317.

Lewis, M.D., Ma, J., Yeo, M., Carrasco, H.J., Llewellyn, M.S., Miles, M.A., 2009. Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. Am J Trop Med Hyg 81, 1041-1049.

Marcili, A., Lima, L., Valente, V.C., Valente, S.A., Batista, J.S., Junqueira, A.C., Souza, A.I., da Rosa, J.A., Campaner, M., Lewis, M.D., Llewellyn, M.S., Miles, M.A., Teixeira, M.M., 2009. Comparative phylogeography of Trypanosoma cruzi TcIIc: New hosts, association with terrestrial ecotopes, and spatial clustering. Infect Genet Evol. 9(6):1265-74

Miles, M.A., Llewellyn, M.S., Lewis, M.D., Yeo, M., Baleela, R., Fitzpatrick, S., Gaunt, M.W., Mauricio, I.L., 2009. The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. Parasitology 136, 1509-1528.

Yeo, M., Acosta, N., Llewellyn, M.,Sanchez, H., Adamson, S., Miles, G.A., Lopez, E., Gonzalez, N., Patterson, J.S., Gaunt, M.W., Arias, A.R., Miles, M.A., 2005. Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillos hosts of Trypanosoma cruzi II, including hybrids. Int J Parasitol 35, 225-233.

Yeo, M., Lewis, M.D., Carrasco, H.J., Acosta, N., Llewellyn, M., da Silva Valente, S.A., de Costa Valente, V., de Arias, A.R., Miles, M.A., 2006. Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium. Int J Parasitol 37, 111-120
Kassen, R., Llewellyn, M.,Rainey, P.B., 2004. Ecological constraints on diversification in a model adaptive radiation. Nature 431, 984-988.


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s